quantitative pharmacodynamics
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Summary
Publications
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Publications

QuanDyn™ method

• Koller JM, Vachon MJ, Bretthorst GL, Black KJ. Rapid quantitative pharmacodynamic imaging with Bayesian estimation. Front. Neurosci. 10:144, 2016 Apr 8. Full text. doi: 10.3389/fnins.2016.00144.
• Black KJ, Koller JM, Miller BD. Rapid quantitative pharmacodynamic imaging by a novel method: theory, simulation testing and proof of principle. PeerJ 1:e117, 2013 Aug 1. Full text. doi: 10.7717/peerj.117. PubMed PMID: 23940831; PubMed Central PMCID: PMC3740141.
• Black KJ, Acevedo HK, Koller JM. Dopamine buffering capacity imaging: A pharmacodynamic fMRI method for staging Parkinson disease. Front. Neurol. 2020; 11:370. doi: 10.3389/fneur.2020.00370
• Black KJ, Koller JM, Perlmutter JS. First test of dopamine buffering capacity imaging as a disease severity biomarker in Parkinson disease. Society for Neuroscience annual meeting abstracts, in press [November, 2021].

Related publications

• Miller B, Marks LA, Koller JM, Newman BJ, Bretthorst GL, Black KJ. Prolactin and fMRI response to SKF38393 in the baboon. PeerJ. 2013 Oct 29; 1:e195. Full text. DOI: 10.7717/peerj.195. PubMed PMID: 24255811; PubMed Central PMCID: PMC3817584.
• Black KJ, Koller JM, Campbell MC, Gusnard DA, Bandak SI. Quantification of indirect pathway inhibition by the adenosine A2a antagonist SYN115 in Parkinson disease. J Neurosci. 2010 Dec 1;30(48):16284-92. doi: 10.1523/JNEUROSCI.2590-10.2010. PubMed PMID: 21123574; PubMed Central PMCID: PMC3008651.